5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde CAS 881674-56-2 Vonoprazan Fumarate Intermediate
Sapalai Vonoprazan Fumarate ma Fesoota'iga Tulaga
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Igoa Kemisi | 5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde |
| Synonyms | Vonoprazan Fumarate (TAK-438) Intermediate 3 |
| Numera CAS | 881674-56-2 |
| CAT Numera | RF-PI330 |
| Tulaga Fa'asoa | O lo'o iai fa'aputuga, Fa'ato'a o'o atu i Tone |
| Fuafua mole | C11H8FNO |
| Molecular Weight | 189.19 |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Samasama i le Paila Enaena |
| Lisimea | 122.0~131.0 ℃ |
| Fa'ailoa: RT(HPLC) | Fa'atasi ma le Fa'asinomaga Tulaga |
| Ma'imau ile Fa'amago | ≤0.50% |
| Toega i luga o le mumu | ≤0.50% |
| Mea Fa'atatau | |
| Mama atoatoa | ≥99.0% |
| So'o se Fa'aleaga Ta'itasi | ≤0.50% |
| Aofa'i Fa'aleaga | ≤1.0% |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Intermediate of Vonoprazan Fumarate (TAK-438) (CAS 881681-01-2) |
afifi: Fagu, Ato pepa alumini, pusa pepa, 25kg/Drum, pe tusa ai ma manaoga o tagata faatau.
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5-(2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde (CAS 881674-56-2) galue o se reagent i le saunia synthetic o tala fou pyrrole derivatives e pei o le potassium-competitive acid blocker (P-CAB).5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde ole vaeluaga ole Vonoprazan Fumarate (CAS 1260141-27-2).Vonoprazan fumarate (Takecab®), na maua ma atiina ae e Takeda ma Otsuka, na faʻamaonia e le PMDA o Iapani ia Tesema 2014, ma o loʻo faʻaalia mo le togafitiga o le gastric ulcer, duodenal ulcer ma reflux esophagitis.Vonoprazan fumarate o loʻo i ai se faiga fou o gaioiga e taʻua o le potassium-competitive acid blockers, lea e faʻatauvaʻa faʻalavelave ai le fusifusia o ion potassium i le H +, K + -ATPase (faʻapitoa foi o le pamu proton) i le laasaga mulimuli o le faʻaogaina o le gastric acid i totonu o sela parietal gastric.E le taofia e Vonoprazan le gaioiga o le Na +, K + -ATPase e oʻo lava i faʻatonuga 500 taimi maualuga atu nai lo latou IC50 faʻatatau i gastric H +, K + -ATPase gaioiga.E le gata i lea, o le vailaʻau e le afaina i le gastric secretory state, e le pei o PPI.
